About Clinical Trials

Clinical Trials

Clinical trials provide participants with the opportunity to participate in cancer research and contribute to the development of new therapeutic approaches.

Talk to your doctor about the potential benefits and risks of joining a clinical trial and if you could be an appropriate candidate.

Find out if you may qualify to be a participant by answering a few questions
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What is a Clinical Trial?

Clinical trials are studies that involve research to:

  • evaluate how well a new treatment works
  • discover what side effects it might have
  • learn how a potential new treatment may work in comparison to other available treatments

Health authorities, such as the United States Food and Drug Administration, use the results of these trials to decide whether a potential new treatment should be approved for use outside of a clinical trial.

Clinical trials follow carefully designed research plans, called protocols, that are developed before the trials begin.

Protocols determine:

  • who would be eligible for the trial
  • which established treatments or potential new treatments are being studied
  • what questions the researchers will try to answer
  • how participants will be cared for throughout the trial

Arcus Biosciences Diversity in Clinical Trials

We believe diversity in clinical trials is core to our responsibility to science and society in order to best understand how our potential new treatments affect different populations of people who may benefit from them. We are thoughtfully working to include a diverse group of participants across all our clinical trials globally and in the United States through both community-based and academic sites.

Clinical Trial Phases

When a potential new treatment is studied, it is evaluated in stages, or “phases.” Each phase assesses the potential benefits and risks of the new treatment being studied. This approach provides progressively more data on participants’ responses over time. At every phase, health authorities, study sponsors, and others use the data—among other factors—to determine whether the study should progress to the next phase.

Phase01

Phase 1 trials include a small group of participants, usually fewer than 100. Depending on the trial, participants may include healthy volunteers or people with specific health conditions.

Phase 1 trials study:

  • how a potential new treatment being studied works in the human body
  • side effects that might occur when someone takes the potential new treatment
  • the appropriate dosage of the potential new treatment that should be used in future trials

Phase02
Phase03
Phase04

Clinical Trial Safety

At Arcus, we design clinical trials with participants’ experience and safety in mind.

It’s important for participants to keep the following guidelines in mind:

  • Participants cannot choose the potential new treatment they receive, or the dosage level of the potential new treatment being studied
  • It is not yet known how participants may respond to the potential new treatment being studied, nor how the potential new treatment being studied will compare to currently available treatments
  • Taking part in a trial may require more doctor visits than usual to help monitor a participant's health and response to potential new treatment
  • Clinical trial participation is always voluntary. Participants have the right to leave the study at any time

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What to Expect as a Participant

What to Expect as a Participant

If you would like to be part of an Arcus clinical trial, we encourage you to speak to your doctor about your enrollment eligibility. Once it is determined that you meet the main criteria to enroll, you can expect to go through a series of steps to ensure that the clinical trial is matched to your specific condition.

Find out if you may pre-qualify as a participant by answering a few questions

The Clinical Trial Team

Members of the Clinical Trial Team

The team is dedicated to monitoring the participant's response and safety throughout the trial and recording the outcomes.

Principal Investigator ("PI")

The Principal Investigator is responsible for leading the trial and supervising the team of doctors, nurses, and other healthcare professionals working at the clinical study site.

Study Coordinator

The Study Coordinator is responsible for managing the day-to-day activities at a clinical study site.

Independent ethics committee (or Institutional Review Board – “IRB”)

The independent ethics committee is responsible for monitoring the study, including to ensure that participants' safety and protection are closely followed.

clinical trial team