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Non-small Cell Lung Cancer (NSCLC)

Durvalumab and Domvanalimab:

PACIFIC-8

Trial

Details

Participation

A Phase 3 clinical trial of domvanalimab, paired with existing approved treatment durvalumab (IMFINZIÂ®), after chemotherapy and radiation. The trial will study these treatments in people with non-small cell lung cancer (NSCLC) that cannot be removed with surgery (unresectable).

Upper GI Cancer

Domvanalimab and Zimberelimab:

STAR-221

A Phase 3 clinical trial of domvanalimab and zimberelimab, plus chemotherapy, for people with an upper gastrointestinal tract (GI) cancer that cannot be removed with surgery (unresectable) that has spread to other parts of the body (metastasized).

Domvanalimab, Zimberelimab, and Quemliclustat

EDGE-Lung

A clinical trial of immunotherapy-based treatment combinations for people with advanced non-small cell lung cancer

Domvanalimab and Zimberelimab

ARC-10

STAR-121

A Phase 3 clinical trial of domvanalimab and zimberelimab, plus chemotherapy, in comparison to pembrolizumab (KEYTRUDAÂ®) plus chemotherapy, for people with non-small cell lung cancer (NSCLC) that has metastasized (spread to the other lung or other parts of the body), as an initial treatment.

Quemliclustat, Domvanalimab, and Zimberelimab

EDGE-Gastric

A Phase 2 clinical trial including some combination of quemliclustat, domvanalimab, zimberelimab, and chemotherapy, for people with an upper gastrointestinal tract (GI) cancer (cancer of the stomach or esophagus) that cannot be removed with surgery (unresectable) that has spread to other parts of the body (metastasized).

Lung Cancer

Gastrointestinal Cancers

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Arcus Clinical Trials for Lung and Gastrointestinal Cancers

Lung Cancer

Gastrointestinal Cancers